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Publications
| 1. | Bouxsein M. Bone Structure and Fracture Risk do they go arm in arm? J Bone Miner Res. 2011;26(7)1389-1391. PDF |
| 2. | Kawai M, Breggia AC, Demambro VE, Shen X, Canalis E, Bouxsein ML, Beamer WG, Clemmons DR, Rosen CJ. The heparin-binding domain of IGFBP-2 has IGF binding-independent biologic activity in the growing skeleton. J Biol Chem. 2011, 286 14670-680. PDF |
| 3. | Dufour AB, Roberts B, Broe KE, Kiel DP, Bouxsein ML, Hannan MT. The factor of risk biomechanical approach predicts hip fracture in men and women: The Framingham Study. Osteoporos Int. 2011 (in press, Feb 23) PDF |
| 4. | Kim YM, Demissie S, Eisenberg R, Samelson EJ, Kiel DP, Bouxsein ML. Intra-and inter-reader reliability of semi-automated quantitative morphometry measurements and vertebral fracture assessment using lateral scout views from computed tomography. Osteoporos Int. 2011 (in press, Jan 27) PDF |
| 5. | Craig ZR, Marion SL, Funk JL, Bouxsein ML, Hoyer PB. Retaining ovarian tissue following ovarian failure has limited influence on bone loss in aged mice. J Osteoporos. 2010; Jun 29 PDF |
| 6. | Christiansen BA, Kopperdahl DL, Kiel DP, Keaveny TM, Bouxsein ML. Mechanical contributions of the cortical and trabecular compartments contribute to differences in age-related changes in vertebral body strength in men and women assessed by QCT-based finite element analysis. J Bone Miner Res. 2010; 26(5) 974-983 PDF |
| 7. | Wegrzyn J, Roux JP, Arlot ME, Boutroy S, Vilayphiou N, Guyen O, Delmas PD, Chapurlat R, Bouxsein ML. Determinants of the mechanical behavior of human lumbar vertebrae after simulated mild fracture. J Bone Miner Res. 2010; 25(11) 2324-31 PDF |
| 8. | Follet H, Viguet-Carrin S, Burt-Pichat B, Depalle B, Bala Y, Gineyts E, Munoz F, Arlot M, Boivin G, Chapurlat R, Delmas PD, Bouxsein ML. Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age and architecture on compressive mechanical properties of elderly human vertebral trabecular bone. J Orthop Res. 2011; 29(4):481-8. PDF |
| 9. | Samelson EJ, Christiansen BA, Demissie S, Broe KE, Zhou Y, Meng CA, Yu W, Cheng X, O'Donnell CJ, Hoffmann U, Genant HK, Kiel DP, Bouxsein ML. Reliability of vertebral fracture assessment using multidetector CT lateral scout views: the Framingham Osteoporosis Study. Osteoporos Int. 2011; 22(4):1123-31. PDF |
| 10. | Rizzoli R, Akesson K, Bouxsein M, Kanis JA, Napoli N, Papapoulos S, Reginster JY, Cooper C. Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economics Aspects of Osteoporosis and Osteoarthritis and International Osterporosis Foundation Working Group Report. Osteoporos Int. 2011; 22(2):373-90. PDF |
| 11. | Jones M, Liu JC, Barthel TK, Hussain S, Lovria E, Cheng D, Schoonmaker JA, Mulay S, Ayers DC, Bouxsein ML, Stein GS, Mukherjee S, Lian JB. A Proteasome Inhibitor, Bortezomib, Inhibits Breast Cancer Growth and Reduces Osteolysis by Downregulating Metastatic Genes. Clin Cancer Res. 2010; 16(20): 4978-89. PDF |
| 12. | Iyer S, Christiansen BA, Roberts BJ, Valentine MJ, Manoharan RK, Bouxsein ML. A biomechanical model for estimating loads on thoracic and lumbar vertebrae. Clin Biomech (Bristol, Avon). 2010; 25(9):853-8. PDF
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| 13. | Wegrzyn J, Roux JP, Arlot ME, Boutroy S, Vilayphiou N, Guyen O, Delmas PD, Chapurlat R, Bouxsein ML. Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex-vivo human L3 vertebrae. J Bone Miner Res. 2010; 25(11): 2324-31. PDF |
| 14. | Chantry AD, Heath D, Mulivor AW, Pearsall S, Baud'huin M, Coulton L, Evans H, Abdul N, Werner ED, Bouxsein ML, Key ML, Seehra J, Arnett TR, Vanderkerken K, Croucher P. Inhibiting activin-A signaling stimulates bone formation and prevents cancer induced bone destruction in vivo. J Bone Miner Res. 2010; 25(12): 2633-46. PDF |
| 15. | Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Lang TF, Brown KM, Shane E, Magaziner J, Zimmerman S, Rubin CT. Insights from the conduct of a device trial in older persons: low magnitude mechanical stimulation for musculoskeletal health. Clin Trials. 2010; 7(4):354-67. PDF |
| 16. | Wagner EB, Granzella NP, Saito H, Newman DJ, Young LR, Bouxsein ML. Partial weight suspension: a novel murine model for investigating adaptation to reduced musculoskeletal loading. J Appl Physiol 2010; 109(2):350-7. PDF |
| 17. | Devlin MJ, Cloutier AM, Thomas NA, Panus DA, Lotinun S, Pinz I, Baron R, Rosen CJ, Bouxsein ML. Caloric restriction leads to high marrow adiposity and low bone mass in growing mice. J Bone Miner Res 2010; 25(9):2078-88. PDF |
| 18. | Roberts BJ, Thrall E, Muller J, Bouxsein ML. Comparison of hip fracture risk by femoral aBMD to Comparison of hip fracture risk prediction by femoral BMD and by the factor-of-risk for hip fracture derived from direct measurements of femoral strength. Bone. 2010; 46(3):742-6. PDF |
| 19. | Guo J, Liu M, Yang D, Bouxsein ML, Saito H, Galvin RJ, Kuhstoss SA, Thomas CC, Schipani E, Baron R, Bringhurst FR, Kronenberg HM. Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab 2010; 11(2):161-71. PDF |
| 20. | Lotinun S, Pearsall RS, Davies MV, Marvell TH, Monnell TE, Ucran J, Fajardo RJ, Kumar R, Underwood KW, Seehra J, Bouxsein ML, Baron R 2010 A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone 46(4):1082-8. PDF |
| 21. | Viguet-Carrin S, Follet H, Gineyts E, Roux JP, Munoz F, Chapurlat R, Delmas PD, Bouxsein ML. Association between collagen cross-links and trabecular microarchitecture properties of human vertebral bone. Bone 2010; 46(2):342-7. PDF |
| 22. | Seeherman HJ, Li XJ, Bouxsein ML, Wozney JM. rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model. J Bone Joint Surg (Am). 2010; 92(2):411-26. PDF |
| 23. | Shomento SH, Wan C, Cao X, Faugere MC, Bouxsein ML, Clemens TL, Riddle RC 2010 Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. J Cell Biochem 109(1):196-204. PDF |
| 24. | Guo J, Liu M, Yang D, Bouxsein ML, Thomas CC, Schipani E, Bringhurst FR, Kronenberg HM. Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology 2010; 151(8):3502-13. PDF |
| 25. | Fajardo RJ, Manoharan RK, Pearsall RS, Davies MV, Marvell T, Monnell TE, Ucran JA, Pearsall AE, Khanzode D, Kumar R, Underwood KW, Roberts B, Seehra J, Bouxsein ML. Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis). Bone. 2010; 46(1): 64-71. PDF |
| 26. | Roux J, Wegrzyn J, Arlot M, Guyen O, Delmas P, Chapurlat R, Bouxsein M. Contribution of trabecular and cortical components to biomechanical behavior of human vertebrae: an ex-vivo study. J Bone Miner Res. 2010; 25(2): 356-61. PDF |
| 27. | Fritton JC, Emerton KB, Sun H, Kawashima Y, Mejia W, Wu Y, Rosen CJ, Panus D, Bouxsein ML, Majeska RJ, Schaffler MB, Yakar S. Growth hormone protects against ovariectomy-induced bone loss in states of low circulating IGF-1. J Bone Min Res. 2010; 25(2):235-46. PDF |
| 28. | Borah B, Dufresne T, Nurre J, Phipps R, Chmielewski P, Wagner L, Lundy M, Bouxsein M, Zabeze R, Seeman E. Risedronate reduces intracortical porosity in women with osteoporosis. J Bone Min Res. 2010; 25(1):41-7. PDF |
| 29. | Pozzi S, Vallet S, Mukherjee S, Cirstea D, Vaghela N, Santo L, Rosen E, Ikeda H, Okawa Y, Kiziltepe T, Schoonmaker J, Xie W, Hideshima T, Weller E, Bouxsein ML, Munshi NC, Anderson KC, Raje N. Clin Cancer Res; 15(18): 5829-39. PDF |
| 30. | Sornay-Rendu E, Boutroy S, Munoz F, Bouxsein ML. Cortical and trabecular architecture are altered in postmenopausal women with fractures. Osteop Int 2009; 20(8): 1291-97. PDF |
| 31. | Bouxsein M, Chen P, Glass E, Kallmes D, Delmas P, Mitlak B. Teriparatide and raloxifene reduce the risk of new adjacent vertebral fractures in postmenopausal women with osteoporosis: Results from two randomized, controlled trials. J Bone Jt Surg (Am) 2009; 91(6): 1321-28. PDF |
| 32. | Rozental TD, Vazquez MA, Chacko AT, Ayogu N, Bouxsein ML. Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy. J Hand Surg Am 2009; 34(4): 595-602. PDF |
| 33. | Yakar S, Canalis E, Sun H, Mejia W, Kawashima Y, Nasser P, Courtland HW, Williams V, Bouxsein M, Rosen C, Jepsen KJ. Serum IFG-1 determines skeletal strength by regulating sub-periosteal expansion and trait interactions. J Bone Min Res 2009; 24(8): 1481-92. PDF |
| 34. | Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ, Riggs BL, Amin S, Muller R, Khosla S. Bone structure at the distal radius during adolescent growth. J Bone Min Res 2009; 24(6):1033-42. PDF |
| 35. | Brouwers JEM, Ruchelsman M, van Rietbergen B, Bouxsein ML. Determination of rat vertebral bone compressive fatigue properties in untreated intact rats and zoledronic acid treated, ovariectomized rats. Osteop Int 2009; 20(8):1377-84. PDF |
| 36. | Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL. Beta-arrestin2 regulates RANKL and Ephrins gene expression in response to bone remodeling in mice. J Bone Min Res 2009; 24(5); 775-84. PDF |
| 37. | Nielson CM, Bouxsein ML, Freitas SS, Ensrud KE, Orwoll ES; for the Osteoporotic Fractures in Men (MrOS) Research Group. Trochanteric soft tissue thickness and hip fracture in older men. J Clin Endocrinol Metab 2009; 94(2): 491-6. PDF |
| 38. | Yakar S, Rosen CJ, Bouxsein ML, Sun H, Mejia W, Kawashima Y, Wu Y, Emerton K, Williams V, Jepsen K, Schaffler MB, Majeska RJ, Gavrilova O, Gutierrez M, Hwang D, Pennisi P, Frystyk J, Boisclair Y, Pintar J, Jasper H, Domene H, Cohen P, Clemmons D, Leroith D. Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J 2009; 23(3):709-19. PDF |
| 39. | Fajardo RJ, Cory E, Patel ND, Nazarian A, Laib A, Manoharan RK, Schmitz JE, Desilva JM, Maclatchy LM, Snyder BD, Bouxsein ML. Specimen size and porosity can introduce error into μCT-based tissue mineral density measurements. Bone 2009; 44(1):176-84 PDF |
| 40. | Bouxsein ML, Devlin MD, Glatt V, Dhillon H, Pierroz DP, Ferrari SL. Mice lacking β-adrenergic receptors have increased bone mass, but are not protected from deleterious skeletal effects of ovariectomy. Endocrinology 2009. 150(1): 144-52. PDF |
| 41. | Yu PB, Deng DY, Lai CS, Hong CC, Cuny GD, Bouxsein ML, Hong DW, McManus PM, Katagiri T, Sachidanandan C, Fukuda T, Mishina Y, Peterson RT, Block KD. BMP Type I receptor inhibition prevents ectopic ossification in a mouse model of fibrodysplasia ossificans progressiva. Nature Med 2008; Dec14(12):1363-9. |
| 42. | Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT Jr, Gardella TJ. Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008; 105(43):16525-30. |
| 43. | Melton LJ 3rd, Riggs BL, Leibson CL, Achenbach SJ, Camp JJ, Bouxsein ML, Atkinson EJ, Robb RA, Khosla S. A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab 2008; 93(12): 4804-9 |
| 44. | Brouwers JEM, Ruchelsman R, van Rietbergen B, Bouxsein ML. Influence of early and late zoledronic acid administration on vertebral structure and strength in ovariectomized rats. Calcified Tissue Int 2008; Sep;83(3):186-91. |
| 45. | Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11851-6. |
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46. | Arlot M, Burt-Pichat B, Roux J, Vashisht D, Bouxsein M, Delmas PD. Microarchitecture influences microdamage accumulation in human vertebral trabecular bone. J Bone Min Res 2008; 23(10):1613-8. |
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47. | Ackert-Bicknell CL, Demissie S, de Evsikova CM, Hsu YH, Demambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ. A PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Min Res 2008; 23(9):1398-408. |
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48. | Keaveny TM and Bouxsein ML. Theoretical implications of the biomechanical fracture threshold. J Bone Min Res 2008; 23(10):1541-7. |
| 49. | O'Brien CA, Plotkin LI, Galli C, Goellner JJ, Gortazar AR, Allen MR, Robling A, Bouxsein M, Schipani E, Turner CH, Jilka RL, Weinstein RS, Manolagas SC, Bellido T. Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One 2008 Aug 13; 3 (8) e2942. |
| 50. | Black DM, Bouxsein ML, Marshall LM, Cummings SR, Lang TF, Cauley JA, Ensrud KE, Nielson CM, Orwoll ES. Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using quantitative computed tomography. J Bone Min Res; 2008; 23 (8): 1326-33. |
| 51. | Wright LE, Christian PJ, Rivera Z, Van Alstine WG, Funk JL, Bouxsein ML, Hoyer PB. Comparison of skeletal effects of ovariectomy versus chemically-induced ovarian failure in mice. J Bone Min Res 2008; 23 (8):1296-1303. |
| 52. | Bouxsein ML and Delmas PD. Considerations for development of surrogate endpoints for anti-fracture efficacy of new treatments in osteoporosis: a perspective. J Bone Min Res 2008; 23 (8): 1155-67. |
| 53. | Davey RA, Turner AG, McManus JF, Chiu WSM, Tjahyono F, Moore AJ, Atkins GJ, Anderson PH, Ma C, Glatt V, MacLean HE, Vincent C, Bouxsein M, Morris HA, Findlay DM, Zajac JD. Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. J Bone Min Res 2008; 23 (8); 1182-93. |
| 54. | Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. 2008; J Biol Chem 2008; 283 (30): 21002-10. |
| 55. | Pearsall RA, Canalis E, Corwall-Brady M, Underwood KW, Haigis B, Ucran J, Kumar R, Pobre E, Brinberg A, Werner ED, Glatt V, Stadmeyer L, Smith D, Seehra J, Bouxsein ML. A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci USA 2008; 105 (19): 7082-7. |
| 56. | Rosental TD, Makhni EC, Day CS, Bouxsein ML. Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention. J Bone Joint Surg Am 2008; 90 (5): 953-61. |
| 57. | DeMambro VE, Clemmons Dr, Horton LG, Bouxsein ML, Wood TL, Beamer WG, Canalis E, Rosen CJ. Gender-specific changes in bone turnover and skeletal architecture in ifgbp-2 null mice. Endocrinology 2008; 149(5): 2051-61. |
| 58. | Black DM, Bouxsein ML, Palermo L, McGowan JA, Newitt DC, Rosen E, Majumdar S, Rosen CJ. Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling. J Clin Endocrinol Metab 2008; 93 (6): 2166-72. |
| 59. | McManus JF, Davey RA, Maclean HE, Doust EA, Chia WS, Sims NA, Bouxsein ML, Glatt V, Zajac JD, Danks JA. Intermittent Fugu parthyroid hormone 1 (1-34) is an anabolic bone agent in young male rats and osteopenic ovariectomized rats. Bone 2008; 42 (6): 1164-74. |
| 60. | Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Inv 2008; 118 (2): 491-504. |
| 61. | Boutroy S, van Rietbergen B, Sornay-Rendu E, Munoz F, Bouxsein ML, Delmas PD. Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Min Res 2008; 23 (3): 392-99. |
| 62. | Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA, Vrahas MS, Bouxsein ML, Evans CH. Delayed administration of adenoviral BMP-2 improves the formation of bone in osseous defects. Gene Ther 2007; 14 (13): 1039-44. |
| 63. | Betz VM, Betz OB, Glatt V, Gerstenfeld LC, Einhorn TA, Bouxsein ML, Vrahas MS, Evans CH. Healing of segmental bone defects by direct percutaneous gene delivery: Effect of vector dose. Hum Gene Ther 2007; 18 (10): 907-15. |
| 64. | Melton LJ, Riggs BL, Keaveny TM, Achenbach SJ, Hoffman PF, Camp JJ, Rouleau PA, Bouxsein ML, Amin S, Atkinson EJ, Robb RA, Khosla S. Structural determinants of vertebral fracture risk. J Bone Min Res 2007, 22 (12): 1885-92. |
| 65. | Kostenuik P, Ferrari S, Pierroz D, Bouxsein M, Morony S, Warmington KS, Adamu S, Geng Z, Grisanti M, Shalhoub V, Martin S, Biddlecome G, Shimamoto G, Boone T, Shen V.Lacey D. Infrequent delivery of a long-acting PTH-Fc fusion protein has potent anabolic effects on cortical and cancellous bone. J Bone Min Res 2007; 22 (10): 1534-47. |
| 66. | Melton LJ, Riggs BL, van Lenthe GH, Achenbach SJ, Muller R, Bouxsein ML, Amin S, Atkinson EJ, Khosla S. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Min Res 2007; 22(9): 1442-8. |
| 67. | Tsiridis E, Morgan EF, Bancroft JM, Song M, Kain M, Gerstenfeld L, Einhorn TA, Bouxsein ML, Tornetta P. Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing. J Orthop Res 2007; 25 (9): 1193-1203. |
| 68. | Glatt V, Canalis E, Stadmeyer L, Bouxsein ML. Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Min Res 2007; 22 (8): 1197-1207. |
| 69. | Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA, Verhas MS, Bouxsein ML, Evans CH. Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther 2007; 14 (13): 1039-44. |
| 70. | Wang Y, Wan C, Liu X, Cao X, Bouxsein ML, Faugere M-C, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL (2007) The hypoxia-inducible factor pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest 2007; 117(6):1616-26. |
| 71. | Bouxsein ML, Szulc P, Munoz F, Thrall E, Sornay-Rendu E, Delmas PD. Contribution of trochanteric soft tissues to fall force estimates, the factor of risk, and prediction of hip fracture. J Bone Min Res 2007: 22(6): 25-31. |
| 72. | Yang D, Singh R, Divieti P, Guo J, Bouxsein ML, Bringhurst FR. Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone. Bone 2007; 40 (6): 1453-61. |
| 73. | Liu X, Bruxvoort KJ, Zylstra CR, Liu J, Cichowski R, Faugere M-C, Bouxsein ML, Wan C, Williams BO, Clemens TL. Lifelong accumulation of bone in mice lacking Pten in osteoblasts. Proc Natl Acad Sci 2007; 104 (7): 2259-64. |
| 74. | Notini A, McManus JF, Moore A, Bouxsein M, Jimenez M, Chiu WM, Glatt V, Kream BE, Handelsman DJ, Morris H, Zajac JD, Davey RA. Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice. J Bone Min Res 2007; 22 (3): 347-56. |
| 75. | Hsu YH, Xu X, Terwedow HA, Niu T, Hung X, Wu D, Wang L, Brain JD, Bouxsein ML, Cummings SR, Rosen CJ. A large-scale genome-wide linkage analysis for loci linked to bone mineral density at different skeletal sites in extreme selected sibships. J Bone Min Res 2007; 22 (2): 184-194. |
| 76. | Zalloua PA, Hsu YH, Terwedo H, Zang T, Wu D, Tang G, Li Z, Hong X, Azar ST, Wang B, Bouxsein ML, Brain J, Cummings SR, Rosen CJ, Xu X. Impact of seafood and fruit consumption on bone mineral density. Maturitas 2007; 56 (1): 1-11. |
| 77. | Bouxsein ML, Riggs BL, Melton LJ III, Muller JA, Atkinson EJ, Oberg A, Robb RA, Camp JJ, Rouleau PA, McCollough CH, Khosla S. Biomechanical assessment of the age- and sex-related differences vertebral fragility: A population-based study using QCT. J Bone Min Res 2006; 21 (9): 1475-82. |
| 78. | Viguet-Carrin S, Roux JP, Arlot ME, Merabet Z, Leeming J, Byrjalsen I, Delmas PD, Bouxsein ML. Contribution of the advanced glycation endproduct pentosidine and maturation of the collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 2006; 39 (5): 1073-9. |
| 79. | Pierroz DP, Bouxsein ML, Rizzoli R, Ferrari SL. Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice. Bone 2006; 39 (2): 260-7. |
| 80. | Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclair Y, Leroith D, Rosen CJ. The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. Journal of Endocrinol 2006; 189 (2): 289-99. |
| 81. | Garnero P, Borel O, Gineyts E, Duboeuf F, Solberg H, Bouxsein ML, Christiansen C, Delmas PD. Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone. Bone 2006; 38: 300-9. |
| 82. | Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML, Gerstenfeld LC, Einhorn TA, Evans, CH. Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg (Am) 2006; 88:355-65. |
| 83. | Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X. Relationship of body composition, fat mass and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr 2006; 83: 146-54. |
| 84. | Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, Oberg A, Rouleau PA, McCollough CH, Khosla S, Bouxsein ML. Population based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Min Res 2006; 21:315-23. |
| 85. | Seeherman H, Li R, Bouxsein M, Kim H, Li XJ, Smith-Adaline E, Aiolova M, Wozney JM. rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a non-human primate model at multiple treatment times and concentrations. J Bone Jt Surg (Am) 2006; 88: 144-160. |
| 86. | Feng Y, Hsu YH, Terwedow H, Chen C, Xu X, Niu T, Zang T, Wu D, Tang G, Li Z, Hong X, Wang B, Brain JD, Cummings SR, Rosen C, Bouxsein ML, Xu X. Familial aggregation of bone mineral density and bone mineral content in a Chinese population. Osteop Int 2005: 16 (12): 1917-23. |
| 87. | Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In vivo assessment of trabecular microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrin & Metab 2005; 90 (12): 6508-15. |
| 88. | Holmen SL, Zylstra CR, Mukherjee A, Sigler RE, Faugere MC, Bouxsein ML, Deng L, Clemens TL, Williams BO. Essential role of beta-catenin in post-natal bone acquisition. J Biol Chem 2005; 280 (22): 21162-8. |
| 89. | Bouxsein ML, Myers KS, Shultz KL, Donahue LR, Rosen CJ, Beamer WJ. Ovariectomy-induced bone loss varies among inbred strains of mice. J Bone Min Res 2005; 20 (7): 1085-92. |
| 90. | Knopp E, Troiano N, Bouxsein M, Sun BH, Lostritto K, Gundberg C, Dziura J, Insogna K. The effect of aging on the skeletal response to intermittent treatment with parathyroid hormone. Endocrinology 2005; 146: 1983-1990. |
| 91. | Ferrari SL, Pierroz DD, Glatt V, Goddard DS, Bianchi EN, Lin FT, Manen D, Bouxsein ML. Bone response to intermittent parathyroid hormone is altered in mice null for ß-arrestin2. Endocrinology 2005; 146:1854-1862. |
| 92. | Bouxsein ML, Pierroz D, Glatt V, Goddard DS, Cavat F, Rizzoli R, Ferrari SL. Beta-arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Min Res, 2005; 20:635-43. |
| 93. | Rosen CJ, Ackert-Bicknell C, Beamer WG, Nelson T, Adamo M, Cohen P, Bouxsein ML, Horowitz MC. Allelic differences in quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition. Pediatr Nephrol, 2005; 20:255-260. |
| 94. | Rosen CJ, Ackert-Bicknell CL, Adamo ML, Shultz KL, Rubin J, Donahue LR, Horton LG, Delahunty KM, Beamer WG, Sipos J, Clemmons D, Nelson T, Bouxsein ML, Horowitz M. Congenic mice with low serum IGF-1 have increased body fat, reduce bone mineral density, and an altered osteoblast differentiation program. Bone, 2004; 35 (5): 1046-58. |
| 95. | Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S. Population-based study of age and sex differences in bone volumetric density, size, geometry and structure at different skeletal sites. J Bone Min Res 2004; 19:1945-54. |
| 96. | Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghaus BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO. Decreased bone density and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Min Res 2004; 19: 2033-40. |
| 97. | Bouxsein ML, Kaufman J, Tosi L, Cummings S, Lane J, Johnell O. Recommendations for care of the osteoporotic fracture patient to reduce the risk of future fracture. J Am Acad Orthop Surg 2004; 12 (6): 385-95. |
| 98. | Seeherman H, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM. Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy healing in a nonhuman primate model. J Bone Jt Surg 2004 ; 86-A: 1961-72. |
| 99. | Bertone AL, Pittman DD, Bouxsein ML, Li J, Clancy B, Seeherman HJ. Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model. J Orthop Res 2004; 22: 1261-70. |
| 100. | Johnston JD, Small CF, Bouxsein ML, Pichora DR. Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the hand. J Orthop Res 2004; 22 (4): 867-871. |
| 101. | Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill G, Müller RA, Beamer, WG. Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Min Res 2004; 19: 587-599. |
| 102. | Kacena M, Shivdasani RA, Wilson K, Yougen X, Troiano N, Nazarian A, Gundberg C, Bouxsein ML, Lorenzo JA, Horowitz MC. Unsuspected megakaryocyte-osteoblast interaction revealed through increased bone formation in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Min Res 2004; 19:652-660. |
| 103. | Yakar S, Setser J, Zhao H, Atannard B, Haluzik M, Glatt V, Bouxsein M, Kopchick J, LeRoith D. Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1 deficient mice. J Clin Invest 2004; 113: 96-105. |
| 104. | Tingart MJ, Bouxsein ML, Zurakowski DE, Warner JJP, Apreleva M. Three-dimensional distribution of bone density in the proximal humerus. Calcif Tissue Int 2003; 73 (6): 531-6. |
| 105. | Li RH, Bouxsein ML, Blake CA, D'August D, Li XJ, Wozney JM, Kim H, Seeherman, HJ. rhBMP-2 injected in a calcium phosphate paste (a-BSM) accelerates healing in the rabbit ulnar osteotomy model. J Orthop Res 2003; 21 (6): 997-1004. |
| 106. | Turner CH, Sun Q, Schriefer J, Pitner N, Price R, Bouxsein ML, Rosen CJ, Donahue LR, Shultz KL, Beamer WG. Congenic mice reveal gender-specific genetic regulation of femoral structure and strength. Calcif Tissue Int 2003; 73 (3): 297-303. |
| 107. | Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ. The effects of PTH and alendronate alone or in combination in post-menopausal osteoporosis. N Engl J Med 2003; 349 (13): 1207-1215. |
| 108. | Einhorn TA, Majeska RJ, Mohaideen A, Kagel EM, Bouxsein ML, Turek TJ, Wozney JM. A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Jt Surg 2003; 85-A: 1425-35. |
| 109. | Bonner FJ, Sinaki M, Grabois M, Shipp KM, Lane JM, Lindsay R, Gold DT, Cosman F, Bouxsein ML, Weinstein JN, Gallagher RM, Melton LJ, Salcido RS, Gordon SL. Health professional's guide to rehabilitation of the patient with osteoporosis. Osteoporosis Int 2003; 14 (suppl 2): S1-S22. |
| 110. | Babij P, Zhao W, Small C, Reddy PS, Yaworsky PJ, Bouxsein M, Bodine PVN, Robinson JA, Moran RA, Kharode Y, Bex F. High bone mass in transgenic mice expressing a mutant human low-density lipoprotein receptor related protein 5 (LRP5). J Bone Min Res 2003; 18: 960-974. |
| 111. | Muller ME, Webber CE, Bouxsein ML. Predicting the failure load of the distal radius. Osteoporosis Int 2003; 14: 345-52. |
| 112. | Zhang M, Xuan S, Bouxsein ML, von Stechow D, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL. Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF-1 signaling in bone matrix mineralization. J Biol Chem 2002; 277 (46): 44005-12. |
| 113. | Shultz K, Donahue LR, Bouxsein ML, Baylink D, Rosen CJ, Beamer WG. Genetic decomposition of quantitative trait loci for high and low volumetric bone mineral density using congenic strains of mice. J Bone Min Res 2003; 18 (2) 175-85. |
| 114. | Li G, Bouxsein ML, Luppen C, Li XJ, Wood M, Seeherman HJ, Wozney JM, Simpson H. Bone consolidation in enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res 2002; 20: 779-788. |
| 115. | Nicholson PHF and Bouxsein ML. Bone marrow influences quantitative ultrasound measurements in human cancellous bone. Ultrasound in Medicine and Biology 2002; 28: 369-75. |
| 116. | Nicholson PHF, Bouxsein ML. Effect of temperature on ultrasonic properties of the calcaneus in situ. Osteoporosis Int 2002; 13 (11): 888-892. |
| 117. | Bouxsein ML, Palermo L, Yeung C, Black DM. Digital x-ray radiogrammetry predicts hip, wrist and vertebral fracture risk in elderly women: A prospective analysis from the Study of Osteoporotic Fractures. Osteoporosis Int 2002; 13: 358-365. |
| 118. | Bouxsein ML, Rosen CJ, Ackert CA, Shultz KL, Donahue LR, Adamo M, Powell DR. Turner CH, Müller RA, Beamer WG. Testing the relationship of IGF-1 to bone mineral density, skeletal morphology and fragility in vivo: Generation of a new congenic mouse strain. J Bone Min Res 2002; 17: 570-579. |
| 119. | Luppen CA, Blake CA, Ammirati KM, Stevens ML, Li XJ, Seeherman HJ, Wozney JM, Bouxsein ML. rhBMP-2 enhances osteotomy healing in glucocorticoid treated rabbits. J Bone Min Res 2002; 17: 301-310. |
| 120. | Bouxsein ML, Turek TJ, Blake CA, Stevens ML, Li XJ, Seeherman HJ, Wozney JM. Recombinant human bone morphogenetic protein-2 accelerates osteotomy healing in rabbit model. J Bone Jt Surgery 2001; 83-A: 1219-1230. |
| 121. | Turner CHT, Hsieh Y-F, Müller R, Bouxsein ML, Rosen CJ, McCrann ME, Donahue LR, Beamer WG. Variation in bone biomechanical properties, microstructure and density in BxH recombinant inbred mice. J Bone Min Res. 2001; 16: 206-213. |
| 122. | Nicholson PHF, Bouxsein ML. Quantitative ultrasound does not reflect mechanically induced damage in cancellous bone. J Bone Min Res 2000; 15:2467-2472. |
| 123. | McClean RR, Hannan MT, Epstein BE, Bouxsein ML, Cupples LA, Murabito J, Kiel DP. Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return. Am J Epidemiology 2000; 151: 689-692. |
| 124. | Nicholson PHF, Strelitzki R, Cleveland RO, Bouxsein ML. Scattering of ultrasound in cancellous bone: fundamental concepts and predictions from a theoretical model. J Biomechanics 2000; 33 (4): 503-506. |
| 125. | Turner CHT, Hsieh Y-F, Müller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Min Res 2000; 15: 1126-1131. |
| 126. | Bouxsein ML, Parker RA, Greenspan SL. Forearm bone mineral density cannot be used to predict the response to alendronate therapy. Osteoporosis Int 2000; 10: 505-509. |
| 127. | Bouxsein ML, Coan BS, Lee SC. Prediction of femoral strength by bone mineral density and quantitative ultrasound measurements of the heel and tibia. Bone 1999; 25: 49-54. |
| 128. | Oden ZM, Selvitelli DM, Bouxsein ML. Effect of local density changes on the failure load of the proximal femur. J Orthop Res 1999; 16:661-667. |
| 129. | Michaeli DA, Mirshahi A, Singer F, Rapa F, Plass D, Bouxsein M. A new x-ray based osteoporosis screening tool provides accurate and precise assessment of phalanx bone mineral content. J Clin Densitometry 1999; 2:23-30. |
| 130. | Bouxsein ML, Michaeli DA, Plass DB, Schick DA, Melton ME. Precision and accuracy of computed digital absorptiometry (CDA) for assessment of bone density of the hand. Osteoporosis Int 1997; 7: 444-449. |
| 131. | Greenspan SL, Bouxsein ML, Melton ME, Kolodny AH, Clair JH, DeLuca PT, Stek M, Faulkner KG, Orwoll ES. Precision and discriminatory ability of calcaneal bone assessment techniques. J Bone Min Res 1997; 12: 1303-1313. |
| 132. | Lee SC, Coan BS, Bouxsein ML. Longitudinal ultrasound velocity of the tibia predicts the material properties of tibial cortical bone. Bone 1996; 21: 119-125. |
| 133. | Bouxsein ML, Radloff SE. Quantitative ultrasound of the calcaneus reflects the mechanical properties of calcaneal trabecular bone. J Bone Min Res 1996; 12: 839-846. |
| 134. | Moro M, Hecker AT, Bouxsein ML, Myers ER. Failure load of thoracic vertebrae correlates with lumbar bone mineral density measure by DXA. Calcif Tissue Int 1995; 56: 206-209. |
| 135. | Bouxsein ML, Courtney AC, Hayes WC. Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs. Calcif Tissue Int 1995; 56: 99-103. |
| 136. | Bouxsein ML, Myburgh KH, van der Meulen MCH, Lindenberger E, Marcus R. Age-related differences in cross-sectional geometry of the forearm bones in healthy women. Calcif Tissue Int 1994; 54:113-118. |
| 137. | Carter DR, Bouxsein ML, Marcus R. New interpretations of projected bone densitometry data. J Bone Min Res 1992; 7: 137-145. |
| 138. | Snow-Harter C, Bouxsein ML, Lewis BT, Carter DR, Marcus R. Effects of resistance and endurance exercise on bone mineral status of young women: A randomized exercise intervention trial. J Bone Min Res 1992; 7: 761-769. |
| 139. | Snow-Harter C, Bouxsein M, Lewis B, Charette S, Weinstein P, Marcus R. Muscle strength as a predictor of bone mineral density in young women. J Bone Min Res 1990; 5: 589-595. |
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